Polarity Establishment and Maintenance in Ascidian Notochord

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Basic principles of polarity establishment and maintenance

Institute of Developmental Biology and Cancer Research, CNRS UMR6543, Université de Nice Sophia-Antipolis, Parc Valrose, 06108 Nice Cedex 2, France Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA Corresponding author. Tel: +33 492 07 6425; Fax: +33 492 07 6466; E-mail: [email protected] Corresponding author. Tel: +1 410 516 6026; Fax: ...

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Ascidian prickle Regulates Both Mediolateral and Anterior-Posterior Cell Polarity of Notochord Cells

The ascidian notochord follows a morphogenetic program that includes convergent extension (C/E), followed by anterior-posterior (A/P) elongation [1-4]. As described here, developing notochord cells show polarity first in the mediolateral (M/L) axis during C/E, and subsequently in the A/P axis during elongation. Previous embryological studies [3] have shown that contact with neighboring tissues ...

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Polarity in filamentous fungi: establishment, maintenance and new axes.

Germ tube emergence in filamentous fungi appears to be similar to bud emergence in yeast. Several key proteins (e.g. Cdc42, septins, Bni1 formin, Rho1 and Rho3) play common roles in polarity establishment and early polarity maintenance in both processes. Although germ tube extension, which can be thought of as extreme polarity maintenance, uses some of the same genes, they are likely to be regu...

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Aspergillus nidulans swo mutants show defects in polarity establishment, polarity maintenance and hyphal morphogenesis.

When the spores of filamentous fungi break dormancy, they grow isotropically, adding cell wall material uniformly in every direction. Later they switch to polarized growth, with new material added to the tip of an emerging germ tube. To identify genes involved in the synthesis and localization of cell wall material in filamentous fungi, we screened a collection of temperature-sensitive Aspergil...

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Brachyury downstream notochord differentiation in the ascidian embryo.

The ascidian tadpole represents the most simplified chordate body plan. It contains a notochord composed of just 40 cells, but as in vertebrates Brachyury is essential for notochord differentiation. Here, we show that the misexpression of the Brachyury gene (Ci-Bra) of Ciona intestinalis is sufficient to transform endoderm into notochord. Subtractive hybridization screens were conducted to iden...

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ژورنال

عنوان ژورنال: Frontiers in Cell and Developmental Biology

سال: 2020

ISSN: 2296-634X

DOI: 10.3389/fcell.2020.597446